High throughput screening technology is based on experimental methods at the molecular and cellular levels, using microplate as the carrier of experimental tools, using sensitive and fast detection instruments to collect experimental results and data, which are analyzed and processed by computers, to collect and test a large number of samples at the same time, obtain a large amount of information, and find valuable information from them. With the continuous development of microbial breeding technology, screening technology determines the efficiency of screening target strains from a huge strain bank.